The role of oxidized albumin in blood cell aggregation disturbance in burn disease.
نویسندگان
چکیده
The burn disease is found to be accompanied by increasing of the level of oxidized proteins of blood serum. We studied the influence of albumin oxidation rate on aggregation of platelets and erythrocytes, disaggregation of erythrocytes. The changes of blood cells aggregation associated with oxidation rate of albumin were found. Possible mechanisms of these effects are discussed.
منابع مشابه
Aggregation of erythrocytes in burn disease.
The manuscript describes experiments designed to examine factors that influence erythrocytes aggregation within the blood of burn patients. Results showed that the rate and degree of erythrocytes aggregation increased significantly in burn patients, and what is especially unfavorable for microcirculation, erythrocytes disaggregation decreased. We show that normalization of blood plasma contents...
متن کاملAssociation of serum melatonin and albumin with cardiovascular disease
Cardiovascular diseases are a major cause of death worldwide. Endothelial dysfunction, inflammatory conditions, and oxidative stress at the forefront of the onset and progression of most cardiovascular diseases specificaly coronary heart disease and heart failure. Melatonin is a type of indole neuroendocrine hormone. It was first found that the regulation of the sleep-wake cycle is regulated...
متن کاملInhibitory effect of Cinnamon on prevention of foam cell formation in platelet and monocytes co-culture
Introduction: Atherosclerosis is one of the leading causes of cardiovascular disease. Following endothelial damage and platelet aggregation in that area and the recruitment of monocytes and their conversion to macrophages, LDL gradually accumulates under the endothelial artery wall and gradually oxidized and convert to oxi-LDL. By swallowing it, the macrophages turn into foam cell and then athe...
متن کاملOxidized LDL is Correlated with Urine Albumin in Type 2 Diabetes Mellitus: A Case-Control Study
Objective: In patients with diabetes mellitus, increased rate of lipoprotein oxidation and oxidative stress have important role in diabetic angiopathy, including nephropathy. We designed a study for comparing the level of Ox-LDL in diabetic patients with Macro-albuminuria, Micro-albuminuria, versus Normo-albuminuric. Materials and Methods: One hundred and thirty five patients with type 2 dia...
متن کاملParenteral Albumin Therapy in Burn Patients: A Randomized Controlled Trial
Background: Administration of albumin for burn patients and its effects on mortality and morbidity has been debated for along time. The aim of this study was to evaluate the effects of albumin administration on wound healing, length of hospital stay, weight change, and mortality of burn patients. Methods: Two matched groups of patients from Shiraz Burn Care Center were randomly selected. The pa...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- International journal of burns and trauma
دوره 3 2 شماره
صفحات -
تاریخ انتشار 2013